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Hampton Inn & Suites St. Louis/South I-55

Hotel Exterior
1 of 12
Trip Advisor average rating of 5 by 1748 reviews


Based on 1,748 guest reviews
Arrival Time
Check-in3 pm
Check-out11 am

Visit the Gateway to the West

Off I-55, we’re 25 minutes from St. Louis Lambert International Airport, and 10 minutes from Mercy Hospital South and the VA Medical Center. The Gateway Arch, downtown, and Anheuser-Busch Brewery are within 20 minutes. Enjoy our indoor pool, fitness center, free WiFi, and free hot breakfast.

Our amenities

  • Connecting Rooms

  • Free hot breakfast

  • Free parking

  • Free WiFi

  • Non-smoking rooms

  • Digital Key

  • Indoor pool

  • Fitness center

  • Pet-friendly rooms

  • Business center

  • Meeting rooms

Hotel Policies

Self parking
Valet parking
Not available
Not available
Not available
In/Out privileges
Other parking Information
Parking Lot

Group travel and events

Our online tools make group travel easy. Reserve 10 – 25 rooms instantly online, then build a free custom website for your guests to book their stay.

Where to find us

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Hampton by Hilton Pin
Hampton Inn & Suites St. Louis/South I-55
4200 MidAmerica Lane, Saint Louis, Missouri, 63129, USA
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